Correcting for multiple-testing in multi-arm trials: is it necessary and is it done?
نویسندگان
چکیده
منابع مشابه
Correcting for multiple-testing in multi-arm trials: is it necessary and is it done?
BACKGROUND Multi-arm trials enable the evaluation of multiple treatments within a single trial. They provide a way of substantially increasing the efficiency of the clinical development process. However, since multi-arm trials test multiple hypotheses, some regulators require that a statistical correction be made to control the chance of making a type-1 error (false-positive). Several conflicti...
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ژورنال
عنوان ژورنال: Trials
سال: 2014
ISSN: 1745-6215
DOI: 10.1186/1745-6215-15-364